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Contributors
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iii-iv
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Contents
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v-vii
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Forthcoming Issues
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viii
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Preface
The April 2012 issue of the Orthopedic Clinics of North America focuses on the various aspects of cartilage in the pediatric knee. Articular cartilage is a dynamic, robust, and complex tissue that int...
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Harpal K. Gahunia
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ix-x
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Articular Cartilage Development: A Molecular Perspective
In this article, development of articular cartilage and endochondral ossification is reviewed, from the perspective of both morphologic aspects of histogenesis and molecular biology, particularly with...
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Facundo Las Heras,
Harpal K. Gahunia,
Kenneth P.H. Pritzker
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155-171
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Structural and Functional Maturation of Distal Femoral Cartilage and Bone During Postnatal Development and Growth in Humans and Mice
23 February 2012
The size and shape of joints markedly affect their biomechanical properties, but the macroscopic 3-dimensional (3-D) mechanism and extent of cartilage and joint maturation during normal growth are lar...
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Elaine F. Chan,
Ricky Harjanto,
Hiroshi Asahara,
Nozomu Inoue,
Koichi Masuda,
William D. Bugbee,
Gary S. Firestein,
Harish S. Hosalkar,
Martin K. Lotz,
Robert L. Sah
et al.
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173-185
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Effect of Exercise on Articular Cartilage
This review primarily focuses on how the macromolecular composition and architecture of articular cartilage and its unique biomechanical properties play a pivotal role in the ability of articular cart...
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Harpal K. Gahunia,
Kenneth P.H. Pritzker
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187-199
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Imaging of Osteochondritis Dissecans
23 February 2012
Osteochondritis dissecans (OCD) is a localized process that affects the subchondral bone and can progress to the overlying articular cartilage. The cause of this lesion remains elusive. With the vague...
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Aiden Moktassi,
Charles A. Popkin,
Lawrence M. White,
M. Lucas Murnaghan
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201-211
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Epidemiology, Pathogenesis, and Imaging of Arthritis in Children
16 March 2012
Juvenile idiopathic arthritis is a broad term used to describe a series of chronic arthritis occurring in children younger than 16 years of age. Even though the cause is not fully understood, several ...
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Ricardo Restrepo,
Edward Y. Lee
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213-225
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Acute Traumatic and Sports-Related Osteochondral Injury of the Pediatric Knee
05 March 2012
Adolescents are predisposed to osteochondral (OC) injuries in the knee. The medial facet of the patella, the femoral trochlea, and the lateral femoral condyle are the most common sites of injury. Most...
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Dennis E. Kramer,
J. Lee Pace
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227-236
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“One Step” Treatment of Juvenile Osteochondritis Dissecans in the Knee: Clinical Results and T2 Mapping Characterization
16 March 2012
Osteochondritis dissecans (OCD) is an increasingly common cause of knee pain and dysfunction among skeletally immature and young adult patients. An ideal treatment strategy with an optimal surgical te...
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Francesca Vannini,
Milva Battaglia,
Roberto Buda,
Marco Cavallo,
Sandro Giannini
et al.
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237-244
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Clinical Relevance of Scaffolds for Cartilage Engineering
09 March 2012
The repair of articular cartilage defects in patients' knees presents a particular challenge to the orthopedic surgeon because cartilage lacks the ability to repair or regenerate itself. Various carti...
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Thomas F. LaPorta,
Alexander Richter,
Nicholas A. Sgaglione,
Daniel A. Grande
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245-254
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Implantation of Orthobiologic, Biodegradable Scaffolds in Osteochondral Repair
16 February 2012
The treatment of articular cartilage lesions is complicated, but novel tissue engineering approaches seem to improve the outcome. A tissue engineering approach is less invasive and reduces surgical ti...
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James H.P. Hui,
Kizher S. Buhary,
Ashwin Chowdhary
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255-261
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Index
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263-267
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